Case Report

Case report of a ‘relatively’ new corneal disease

Dirk J. Booysen, Roland Höllhumer
African Vision and Eye Health | Vol 79, No 1 | a543 | DOI: | © 2020 Dirk J. Booysen, Roland Hollhumer | This work is licensed under CC Attribution 4.0
Submitted: 28 October 2019 | Published: 05 March 2020

About the author(s)

Dirk J. Booysen, Department of Optometry, Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa
Roland Höllhumer, Department of Ophthalmology, University of the Witwatersrand Johannesburg, Johannesburg, South Africa; and, The Cornea Foundation, Johannesburg, South Africa


Peripheral hypertrophic sub-epithelial corneal degeneration was first described in 2003 and involves bilateral, symmetrical, peripheral, hypertrophic and sub-epithelial corneal opacification. The disease affects mostly young white women with light-coloured eyes and must be differentiated from corneal intraepithelial neoplasia, bullous keratopathy, climatic droplet keratopathy, corneal amyloidosis, corneal keloid, hereditary hypertrophic scarring, pseudo-pterygia and Salzmann’s nodular degeneration. This case report serves to highlight the clinical findings.


corneal opacification; sub-epithelial; degeneration; hypertrophic; cornea


Total abstract views: 1998
Total article views: 2760

Crossref Citations

No related citations found.