Original Research

Intraocular pressure in postmenopausal Nigerian women with and without systemic hypertension

J. A. Ebeigbe, P. N. Ebeigbe, A. D. A Ighoroje
African Vision and Eye Health | South African Optometrist: Vol 70, No 3 | a103 | DOI: https://doi.org/10.4102/aveh.v70i3.103 | © 2011 J. A. Ebeigbe, P. N. Ebeigbe, A. D. A Ighoroje | This work is licensed under CC Attribution 4.0
Submitted: 11 December 2011 | Published: 11 December 2011

About the author(s)

J. A. Ebeigbe, Department of Optometry, Faculty of Life Sciences, University of Benin, Nigeria
P. N. Ebeigbe, Department of Obstetrics and Gynaecology, Faculty of Health Sciences, Delta State University, Nigeria
A. D. A Ighoroje, Department of Physiology, School of Basic Medical Sciences, University of Benin

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Background: Mean intraocular pressure (IOP) in postmenopausal women has been reported higher than that in menstruating women. Also, intraocular pressure is said to be positively correlated with systemic blood pressure. No previous study in Nigeria has compared intraocular pressure in postmenopausal women with and without systemic hypertension. Purpose: To investigate the effects of menopause on intraocular pressure in subjects with and without high blood pressure. Methods: Normotensive and hypertensive premenopausal and postmenopausal subjects in the   same agerange of 45 to 55 years were studied. Intraocular pressure was measured with the hand-held Kowa applanation tonometer.  Blood pressure was taken in the sitting position at the right upper arm using a manual mercury sphygmomanometer with the right cuff size. The average of two readings was recorded. Results: Mean IOP for premenopausal normotensive women was 14.58 ± 2.56 mmHg whilethat of postmenopausal normotensive women was16.15 ± 1.80 mmHg (p<0.05).  Also, the difference in mean IOP between premenopausal hypertensive (16.58 ± 3.23 mmHg) and postmenopausal hypertensive women (18.24 ± 3.89 mmHg)
was statistically significant (p<0.05). A statistically significant and positive correlation was observed between IOP and systemic blood pressure in postmenopausal hypertensive women, p<0.05.
Conclusion: Menopause significantly increases intraocular pressure. Mean intraocular pressure of hypertensive postmenopausal women was significantly higher than that of normotensive post-menopausal women, (p<0.05). Knowledge of the normal level of intraocular pressure during various stages of the female reproductive cycle may help during glaucoma screening. (S Afr Optom 2011 70(3) 117-122)


Menopause; intraocular pressure; systemic blood pressure


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